http://www.ncbi.nlm.nih.gov/pubmed/23867186
Blood Transfus. 2014 Jan;12 Suppl 1:s229-34. doi: 10.2450/2013.0293-12. Epub 2013 Jul 3.
Use of platelet-rich plasma in the care of sports injuries: our experience with ultrasound-guided injection.
Blood Transfus. 2014 Jan;12 Suppl 1:s229-34. doi: 10.2450/2013.0293-12. Epub 2013 Jul 3.
Use of platelet-rich plasma in the care of sports injuries: our experience with ultrasound-guided injection.
El uso de plasma rico en plaquetas en el cuidado de las lesiones deportivas: nuestra experiencia con la inyección guiada por ultrasonidoBernuzzi G1, Petraglia F2, Pedrini MF2, De Filippo M3, Pogliacomi F4, Verdano MA4, Costantino C2.
Abstract
BACKGROUND:
Platelet-rich plasma is being used more frequently to promote healing of muscle injuries. The growth factors contained in platelet-rich plasma accelerate physiological healing processes and the use of these factors is simple and minimally invasive. The aim of this study was to demonstrate the efficacy of ultrasound-guided injection of platelet-rich plasma in muscle strains and the absence of side effects.
ANTECEDENTES:
Plasma rico en plaquetas se utiliza con mayor frecuencia para promover la curación de las lesiones musculares. Los factores de crecimiento contenidos en el plasma rico en plaquetas acelerar los procesos de curación fisiológicos y el uso de estos factores es simple y mínimamente invasiva. El objetivo de este estudio fue demostrar la eficacia de la inyección guiada por ultrasonido de plasma rico en plaquetas en las lesiones musculares y la ausencia de efectos secundarios.
MATERIALS AND METHODS:
Fifty-three recreational athletes were enrolled in the study. The patients were recruited from the Emergency Room in the University Hospital at Parma according to a pre-defined protocol. Every patient was assessed by ultrasound imaging to evaluate the extent and degree of muscle injuries. Only grade II lesions were treated with three ultrasound-guided injections of autologous platelet-rich plasma every 7 days. Platelet concentrate was produced according to standard methods, with a 10% variability in platelet count. The platelet gel for clinical use was obtained by adding thrombin to the concentrates under standardised conditions. Outcomes assessed were: pain reduction, muscle function recovery and return to sports activity, ultrasound-imaging tissue healing, relapses, local infections, and any side effect during the treatment.
RESULTS:
In all cases muscle lesions healed fully on ultrasound-imaging, the pain disappeared, and muscle function recovery was documented with a return to sports activity. A single patient had a relapse 1 year after treatment.
DISCUSSION:
Platelet-rich plasma injected into the injury site is one of the most important factors rendering the treatment effective. To maximise its efficacy the preliminary ultrasound must be done accurately to localise the lesion and guide the needle into the corresponding lesion. According to the current results, which document full muscle recovery and no relapse except for one case, platelet-rich plasma ultrasound-guided injection represents a valid mini-invasive treatment for muscle injuries.
El plasma rico en plaquetas se inyecta en el sitio de la lesión es uno de los factores más importantes de representación el tratamiento eficaz. Para maximizar su eficacia el ultrasonido preliminar debe realizarse con precisión para localizar la lesión y guiar la aguja en la lesión correspondiente. De acuerdo con los resultados actuales, que documentan la recuperación muscular completa y sin recaída a excepción de un caso, la inyección guiada por ultrasonido de plasma rico en plaquetas representa un tratamiento mini-invasiva válida para lesiones musculares.
Abstract
BACKGROUND:
Platelet-rich plasma is being used more frequently to promote healing of muscle injuries. The growth factors contained in platelet-rich plasma accelerate physiological healing processes and the use of these factors is simple and minimally invasive. The aim of this study was to demonstrate the efficacy of ultrasound-guided injection of platelet-rich plasma in muscle strains and the absence of side effects.
ANTECEDENTES:
Plasma rico en plaquetas se utiliza con mayor frecuencia para promover la curación de las lesiones musculares. Los factores de crecimiento contenidos en el plasma rico en plaquetas acelerar los procesos de curación fisiológicos y el uso de estos factores es simple y mínimamente invasiva. El objetivo de este estudio fue demostrar la eficacia de la inyección guiada por ultrasonido de plasma rico en plaquetas en las lesiones musculares y la ausencia de efectos secundarios.
MATERIALS AND METHODS:
Fifty-three recreational athletes were enrolled in the study. The patients were recruited from the Emergency Room in the University Hospital at Parma according to a pre-defined protocol. Every patient was assessed by ultrasound imaging to evaluate the extent and degree of muscle injuries. Only grade II lesions were treated with three ultrasound-guided injections of autologous platelet-rich plasma every 7 days. Platelet concentrate was produced according to standard methods, with a 10% variability in platelet count. The platelet gel for clinical use was obtained by adding thrombin to the concentrates under standardised conditions. Outcomes assessed were: pain reduction, muscle function recovery and return to sports activity, ultrasound-imaging tissue healing, relapses, local infections, and any side effect during the treatment.
RESULTS:
In all cases muscle lesions healed fully on ultrasound-imaging, the pain disappeared, and muscle function recovery was documented with a return to sports activity. A single patient had a relapse 1 year after treatment.
DISCUSSION:
Platelet-rich plasma injected into the injury site is one of the most important factors rendering the treatment effective. To maximise its efficacy the preliminary ultrasound must be done accurately to localise the lesion and guide the needle into the corresponding lesion. According to the current results, which document full muscle recovery and no relapse except for one case, platelet-rich plasma ultrasound-guided injection represents a valid mini-invasive treatment for muscle injuries.
El plasma rico en plaquetas se inyecta en el sitio de la lesión es uno de los factores más importantes de representación el tratamiento eficaz. Para maximizar su eficacia el ultrasonido preliminar debe realizarse con precisión para localizar la lesión y guiar la aguja en la lesión correspondiente. De acuerdo con los resultados actuales, que documentan la recuperación muscular completa y sin recaída a excepción de un caso, la inyección guiada por ultrasonido de plasma rico en plaquetas representa un tratamiento mini-invasiva válida para lesiones musculares.
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